Jessica C. Seeliger

Cytoplasmic C-Terminal Domain of the MmpL11 Lipid Transporter Is Required for Interaction with Its Co-cistronic Partner MSMEG_0240 in Mycobacterium smegmatis

Abstract MmpL proteins play an important role in the various mechanisms associated with mycobacterial virulence. Identification of interacting protein partners by classical in vitro methods is hampered by the low solubility of these integral membrane proteins. In this study, we u...

Adapting Architecture: Lipid Membrane Remodeling in Mycobacteria

The mycobacterial cell envelope is a formidable barrier, regarded as one of the most chemically and structurally elaborate architectures in the Bacteria kingdom. Membrane remodeling, defined as changes in membrane lipid composition in response to stressors, has been a subject of...