Jennifer Ekua Duker

A narrative review of oral manifestations, genotype–phenotype links, and management in pachyonychia congenita

Objective of study Pachyonychia Congenita (PC) is a rare autosomal dominant genodermatosis caused by mutations in keratin genes (KRT6A, KRT6B, KRT6C, KRT16, KRT17). Oral manifestations are seen in more than half of patients, most often as leukokeratosis, natal teeth, or laryngeal...