Author
Jemma Gullick
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Recent research
- Health & MedicineOpen access
Synthesis of Glycopeptide Antibiotic Peptide Substrates Using Knorr‐Pyrazole Chemistry
The glycopeptide antibiotics (GPAs) remain clinical antibiotics used against drug‐resistant Gram‐positive infections. The discovery of GPAs continues, with new type IIa and V GPAs, the kineomicins, the rimomycins, and corbomycin, being recently identified. Despite this larger rep...
- Health & MedicineOpen access
Staphylococcus aureus strains have emerged with resistance mechanisms that reduce the efficacy of last resort antibiotics and evade the immune system. One strategy to combat antimicrobial resistance is to modulate host immunity to eliminate infections more effectively. This has l...