Jean-Marc Goldsmith

Ampicillin Resistance is Increased in Escherichia coli K12 relA and spoT mutants but Sub-inhibitory Pretreatment Does Not Induce Adaptive Resistance

The genes relA and spoT of Escherichia coli are required for the production of guanosine tetraphosphate, a critical molecule for the adoption of a stringent state that minimizes harm during metabolic and environmental stress. Subinhibitory treatments of antibiotics have been show...