J.C. Galvez-Ruiz

Terminalia buceras (Syn. Bucida buceras) and Retinal Oxidative Stress: A Critical Review of Published Evidence and Its Relevance to Dry Age-Related Macular Degeneration

Dry age-related macular degeneration (dAMD) is a multifactorial retinal disorder involving oxidative stress, mitochondrial dysfunction, chronic para-inflammation, complement dysregulation, and progressive retinal pigment epithelium (RPE) failure. This critical review evaluates th...

Selective Cytotoxic Activity of Derivatives of the Natural Alkaloid Tetrandrine Against Cancer Cell Lines: In Vitro and In Silico Studies

Tetrandrine (TET) is a bisbenzylisoquinoline alkaloid with promising anticancer activity, although its limited selectivity toward malignant over non-cancerous cells restricts its therapeutic potential. A series of mono- and bis-N-substituted tetrandrine derivatives was therefore...