Jason Mercer

High-content image-based screening reveals vaccinia virus membrane proteins as potential regulators of LC3 lipidation

Autophagy is a catabolic process used for the degradation of organelles and proteins, and it also functions as a cellular defense mechanism, known as xenophagy, during infection. Vaccinia virus (VACV), the prototypic poxvirus, replicates exclusively in the cytoplasm of host cells...