Jan Padeken

DVE-1 is a telomere-binding protein and links the NuRD complex to telomere regulation in C. elegans

Telomeres are repetitive DNA sequences at the ends of linear chromosomes bound by specialized proteins. In our previous quantitative proteomics screen for telomere-binding proteins of Caenorhabditis elegans , we identified DVE-1, a homolog of mammalian SATB proteins and a transcr...