Jamil Kraı̈em

Taguchi-Optimized Green Synthesis of a Novel Nickel-bis-thiazoline Complex: A Bifunctional Platform for Sustainable Ullmann-type N-Arylation and Antibacterial Applications

A novel bis-thiazoline ligand and its nickel(II) complex were synthesized via an environmentally benign and mild protocol.Synthesis parameters were systematically optimized using the Taguchi Design of Experiments (DoE), achieving high yields (> 98%) and ensuring a scalable, repro...