James W. Fawcett

4‐Methylumbelliferone Restores Age‐Related Changes in Perineuronal Nets, Memory, and Neuroinflammation

Aging-associated cognitive decline is closely linked to dysregulated glial activity and chronic neuroinflammation, which together constrain neuronal plasticity. Astrocytes and microglia are key regulators of the brain extracellular matrix (ECM), including perineuronal nets (PNNs)...