James V. Sugai

Systemic RVX ‐208 Attenuates Experimental Periodontitis Through Inflammatory Host Modulation

AIMS: This study investigated whether systemic treatment of RVX-208, a selective BET protein inhibitor, could ameliorate experimental periodontitis in a prophylactic setting and examined transcriptomic changes associated with RVX-208 in vitro. METHODS: Porphyromonas gingivalis (P...