Jaime G. Manzaneque-Luengo Bensusan

Existing molecular biology indicates a path to biological immortality

This preprint argues that complementary single strand lesions (CSSLs) are the primary irreversible form of nuclear DNA damage driving aging. A simple Bayesian model using average literature values for daily new damage (~70,000 lesions/cell) and steady damage (~38,000 lesions/cell...