Jaime E. C. Hallak

Evaluation of the Effects of Different Doses of Ayahuasca on Intelligence and Verbal Memory in Healthy Volunteers

Background: Observational studies with ritual ayahuasca users suggest that experienced users tend to have better cognitive performance, while novice users may experience transient impairments, particularly in working memory. However, no randomized clinical trials have systematica...

Differential Effects of Cannabidiol and Cannabigerol on Cognition, Neuroinflammation, and Blood–Brain Barrier Integrity in a Rat Model of Iron Overload

Abstract Iron is an essential micronutrient for brain development, participating in mitochondrial respiration, myelination, and neurotransmitter synthesis. However, previous studies have demonstrated that excessive iron during early postnatal life induces oxidative reactions, lea...