Jagadish Singh

Design, synthesis, SAR, in silico and in vitro evaluation of 1, 3, 4-oxadiazole derivatives against breast cancer

The 1,3,4-oxadiazole scaffold is well recognized for its anticancer potential. Based on our previous work, we designed and synthesized nine 1,3,4-oxadiazole derivatives (R1–R9) via Schiff base formation followed by cyclization. The compounds were characterized by FT-IR, ¹H NMR, a...