Jacqueline J. Horsford

The Terrain–Timing Model: A Systems Framework for Biological Coherence

Core Systems Focus: Establishes the universal conceptual and relational architecture of the model, independent of any single disease state. Synopsis: Paper 1 argues that biological function depends on more than the presence or normal abundance of molecular components. It proposes...

Modes of Temporal Incoherence

Core Systems Focus: Provides the functional taxonomy for timing failures across biological signaling and recovery tracks.Synopsis: This monograph distinguishes Phase Incoherence, Kinetic Incoherence, and Continuity Incoherence, shifting attention from whether a biological event o...

The Biological Event Horizon: A Terrain–Timing Theory of Reversibility

Core Systems Focus: Characterizes system execution thresholds, hysteresis, and the transition from recoverable perturbation to state-maintained dysfunction. Synopsis: This paper operationalizes the Biological Event Horizon as the transition at which removing an initiating perturb...