Jacob E. Lemieux

Subtype-specific differences in susceptibility to monoclonal antibodies and vaccines among contemporary RSV-A and RSV-B isolates

ABSTRACT Respiratory syncytial virus (RSV) continues to circulate at high levels despite the introduction of new monoclonal antibodies (mAbs) and vaccines targeting the pre-fusion F (pre-F) protein. We analyzed the viral genome sequences of 133 RSV clinical samples collected duri...

Streamlined CRISPR-based assays for detection and subtyping of H5 and H7 avian influenza

Avian influenza viruses (AIVs) are zoonotic pathogens that pose an increasing global threat due to their potential for significant economic losses in agriculture, and the risk of a pandemic should human-to-human transmission occur. In light of this, we need rapid, sensitive, and...