Izhak Kehat

Single-Molecule Imaging Reveals ERK-Dependent Spatial Translation in Cardiomyocytes

BACKGROUND: Translational control of gene expression is crucial in cardiomyocytes, particularly in response to hypertrophic stimuli. The ERK (extracellular signal-regulated kinase) pathway plays a key role in inducing cardiac hypertrophy and regulating specific protein translatio...