Ivana Pajic-Lijakovic

Piezo1 footprint nanoarchitecture: from individual channels to collective behaviour and from outward to inward curvature

Piezo1 acts as a key architect of the cell membrane, generating a curved nanodome that extends beyond the protein trimer itself. Although Piezo1 intrinsically favours an outward (convex) membrane footprint, recent high-resolution studies have revealed that clustered channels can...