Iván Pérez-Núñez

METTL3-mediated m 6 A modification of DNMT1 enhances ovarian cancer progression

Abstract High-grade serous carcinoma (HGSC), the most lethal subtype of ovarian cancer, is often diagnosed at advanced stages owing to its asymptomatic progression and lack of early detection markers. In this study, we identified a critical oncogenic role of the RNA methyltransfe...