Iulia Georgiana Bogdan

Clinical Efficacy and Safety of Fosmanogepix in Patients with Invasive and Refractory Fungal Infections: A Systematic Review

Background: Fosmanogepix is a first-in-class Gwt1 inhibitor with oral and intravenous formulations and broad in vitro activity, but its clinical evidence is scattered across small trials and case reports. We reviewed all identifiable human data from the searched sources on its ef...

Olorofim for Invasive Fungal Diseases in Patients with Limited or No Treatment Options: A Systematic Review

Olorofim, the first orotomide antifungal, is active against Aspergillus spp., Lomentospora prolificans, Scedosporium spp. and Coccidioides spp. We reviewed published clinical reports of olorofim in invasive fungal disease (IFD) with limited or no treatment options. PubMed/MEDLINE...