王木强

Machine Learning Empowers Enzyme Discovery, Structure Prediction, Engineering, and Design

Abstract Enzymes are efficient and selective biocatalysts, yet obtaining enzymes with desired properties remains challenging due to vast sequence spaces, incomplete functional annotation, limited structural information, and costly experimental screening. Machine learning (ML) off...

Recyclable and Scale-Up-Compatible Ag/I-Mediated Synthesis of Aryl α-Keto Acids from Terminal Alkenes Using Dioxygen as the Terminal Oxidant

Abstract α-Keto acids are vital intermediates in organic synthesis and biological metabolism, yet existing synthetic methods suffer from low efficiency, harsh conditions, or poor environmental compatibility. Herein, we report a recyclable and scale-up-compatible Ag/I-mediated aer...