宋伟航

The AURKA–PTTG1 signaling axis induces enzalutamide resistance in prostate cancer

Background Prostate cancer (PCa), a common male malignant tumor, often develops resistance to the androgen receptor inhibitor enzalutamide (ENZ). Despite its established oncogenic role, pituitary tumor-transforming gene 1 (PTTG1)’s specific function and regulatory mechanism in EN...