Author
山松 高
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Recent research
- BiologyOpen access
Nucleosomes and IDRs suppress promiscuous GCN4 binding on minichromosomes
Abstract Eukaryotic sequence-specific transcription factors (TFs) must find their cognate DNA targets hidden in genomic chromatin amid an excess of nonspecific sequences and degenerate motifs. Although static TF interactions with nucleosomal targets have been elucidated, how TFs...