István Szegedi

Unveiling Cerebrospinal Fluid Protein Biomarkers in Pediatric Acute Lymphoblastic Leukemia Using a Proximity Extension Assay

Abstract Acute lymphoblastic leukemia (ALL) is a heterogeneous pediatric malignancy where relapse and central nervous system (CNS) involvement remain critical challenges. We combined high-throughput proteomics and machine learning (ML) to identify cerebrospinal fluid (CSF) biomar...