Isaac Shiri

Accuracy of CT-derived interarterial and intramural anomalous coronary arteries anatomy compared with 3D-reconstructed IVUS in-vivo reference

In anomalous aortic origin of a coronary artery (AAOCA), coronary CT angiography (CCTA) is the primary tool for anatomical assessment. However, CCTA measurements lack validation against a high-resolution in-vivo standard. To assess CCTA reliability for lumen dimensions and intram...

Reconstruction-informed and multidomain deep learning for generalizable CT-free attenuation correction in SPECT myocardial perfusion imaging.

Purpose Deep learning (DL) has shown promise in enabling attenuation correction (AC) for SPECT myocardial perfusion imaging (MPI) without relying on anatomical information or CT-derived attenuation maps (ATMs). We introduce a novel reconstruction-informed and multidomain (RIMD) D...

Fluid dynamics-informed CCTA-derived geometric parameters in right coronary artery anomalies predict abnormal invasive Adenosine-FFR and Dobutamine-FFR.

Background Traditional anatomical assessment of stenosis in right anomalous aortic origin of coronary arteries (R-AAOCA) may not capture the complex, eccentrically shaped lumen and its perimeter-dependent resistance, and may therefore underestimate flow limitation. R-AAOCA involv...