Ingrid Garajová

Longitudinal Circulating Nerve Growth Factor in Pancreatic Ductal Adenocarcinoma: An Exploratory Study of Postoperative Recurrence and First-Line Disease Control

Nerve growth factor (NGF) signaling is involved in pancreatic ductal adenocarcinoma (PDAC) neurotropism, perineural invasion, pain, and tumor-stromal crosstalk, but its value as a circulating biomarker remains poorly defined. We retrospectively analyzed 51 patients with PDAC who...

Prognostic Role of Adverse Events in a Worldwide Population of Patients with Biliary Tract Cancer Treated with Chemo-Immunotherapy

Background: Biliary tract cancers (BTCs) are aggressive malignancies with limited treatment options. The addition of durvalumab or pembrolizumab to cisplatin–gemcitabine improves overall survival (OS), but validated biomarkers of benefit remain limited. Immune-mediated adverse ev...