Ichiro Hisatome

A case of renal hypouricemia type 1 associated with compound heterozygous URAT1/SLC22A12 variants A209V and F379L: clinical evidence for their pathogenic significance

Abstract Renal hypouricemia (RHUC) is an inherited renal tubular disorder characterized by low serum uric acid levels and excessive urinary uric acid excretion due to impaired urate reabsorption in proximal tubules. Type 1 RHUC (RHUC1) is caused by pathogenic variants in URAT1/SL...

Association between serum uric acid and muscle function in underweight young women: An exploratory cross-sectional study

Introduction Uric acid (UA), a major endogenous antioxidant involved in oxidative stress regulation and energy metabolism, has been linked to skeletal muscle health. However, evidence regarding its association with muscle function and muscle mass in underweight young women is lim...