Ian S. Roberts

In vitro and in vivo functional roles of three region 1 promoters in Escherichia coli K1 capsule gene cluster

Capsular polysaccharides are key virulence determinants in extraintestinal pathogenic Escherichia coli , protecting bacteria from host immune defences while modulating interactions with host tissues. In group 2 capsule gene clusters, transcription of region 1 genes required for c...