Huiguang Yu

Controlled Epoxide-Enabled Formal Oxygen Insertion of Indenones to Isocoumarins

Abstract Regioselective oxygen insertion into sp2-rich carbonyl scaffolds remains challenging because Baeyer–Villiger oxidation relies on migratory aptitude. Here, we translate an aziridine-based nitrogen-insertion platform to an epoxide-enabled oxygen-insertion manifold for inde...