Hui Wei

A Theranostic Nanozyme for Osteoarthritis Treatment and Glycosaminoglycan-Targeted Diagnosis of Cartilage Pathology

Abstract The lack of vascular and neural innervations in cartilage often results in poor drug delivery and penetration, compromising the efficacy of current therapeutics. To tackle this clinical challenge, we designed positively charged manganese-doped CeO2 nanozymes that combine...

Machine Learning-Assisted Nanozyme–Porphyrin Dual-Channel Sensor Array for Glycosaminoglycan Pattern Recognition

Abstract Selective discrimination of glycosaminoglycans (GAGs) is crucial for drug safety and quality control but remains challenging because GAGs share similar disaccharide repeating units and overlapping polyanionic features. Nanozyme-based sensor arrays offer a cross-reactive...