Huang Liu

Defective PDZK1 palmitoylation impairs epididymosome-mediated cholesterol transport and contributes to asthenozoospermia

Asthenozoospermia, a leading cause of male infertility characterized by impaired sperm motility, involves dysregulated cholesterol efflux during epididymal maturation, yet the underlying mechanisms remain elusive. Here, we demonstrate that PDZK1 protein level and its palmitoylati...

The role of LncRNA FOXD3-AS1 in multiple human malignancies

Long non-coding RNA (lncRNA) molecules, which are over 200 nucleotides long without protein-coding potential, play crucial roles in various biological processes and the progression of tumors. Emerging evidence shows that lncRNA forkhead box D3 antisense 1 (FOXD3-AS1) is transcrib...