Huan Zhou

Driver gene-based prognostic model benchmarked against machine learning survival models is associated with a CAF–TGFβ–EMT-like phenotype in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is molecularly heterogeneous, limiting conventional prognostic tools. Whole-genome resequencing of six HCC cases was used only to filter candidates. Somatically mutated genes were intersected with HCC-annotated entries from five predefined driver re...