Huai Liu

Development of pathology-responsive Cu-based metal–phenolic nanonetworks for disease-modifying treatment of knee osteoarthritis

Objectives Knee osteoarthritis (KOA) is characterized by chronic inflammation, oxidative stress, and extracellular matrix (ECM) degradation, while current therapies mainly provide symptomatic relief. We developed a pathology-responsive copper-based metal-phenolic nanonetwork (Cu-...