Hu Liu

A hypothalamic circuit links high-fat diet exposure to anxiety-like behavior and anxiety-associated hyperphagia

Obesity and anxiety disorders are frequently comorbid, yet the neural circuit mechanisms linking metabolic and affective states remain incompletely understood. Here, in male mice exposed to long-term high-fat diet, we identify a hypothalamic circuit comprising arcuate nucleus ago...

Rare benzannulated spiroketal dimers from an endophytic Chaetomium sp.

Three undescribed dimeric benzannulated spiroketals (1 − 3) were isolated from the fermented broth of Chaetomium sp. UJN-EF006, an endophytic fungal strain derived from Vaccinium bracteatum. Structures of these distinctive fungal products were elucidated by comprehensive spectros...