Howard A. Young

Patient-Derived Transcriptomics Reveals Distinct Associated IFNγ-Myeloid States and Mitochondrial Complex I Programs in Rheumatoid Arthritis and Osteoarthritis

Background/Objectives: Macrophages are key contributors to the pathogenesis of rheumatoid arthritis (RA) and osteoarthritis (OA), but their disease-associated immunometabolic states remain incompletely understood. Methods: Here, we comparatively analyzed patient-derived transcrip...