Hosup Shim

Transplantation of directly converted HDF-iNSC to the scala tympani of the cochlea increases neural structure and central auditory connection in an auditory neuropathy animal model

Cochlear implants (CIs) provide effective rehabilitation for severe-to-profound hearing loss, yet their success is limited by secondary degeneration of auditory neurons. Direct transdifferentiation, which enables lineage conversion of somatic cells into neural stem cells without...