Hossein Omidi-Ardali

Regulation of Membrane Association and Downstream Effector Interaction of K-Ras by Its Hypervariable Region

The small GTPase Ras, a central switch in signal transduction of cell growth, is a crucial element in the development of many forms of cancer. Recent studies have shown that membrane association of Ras is essential to its downstream effector recruitment and signal transduction. H...