Hongying Wu

Integrated Metabolomic and Metagenomic Profiling Reveals Distinct Microbial–Metabolic Signatures in the Adenoma–Carcinoma Sequence of Colorectal Cancer

Colorectal cancer (CRC) arises via the stepwise adenoma-carcinoma sequence (ACS). Gut microbial dysbiosis and host metabolic reprogramming jointly correlate with CRC onset and advancement, yet their stage-specific crosstalk across ACS remains largely unclear. Limited multi-omics...