Hongyi Tan

Computationally guided hapten design enables a colloidal gold immunochromatographic assay for rapid citalopram detection in water and dietary supplements

Citalopram, a widely prescribed selective serotonin reuptake inhibitor (SSRI), has emerged as an environmental and food contaminant owing to its extensive consumption and incomplete removal during wastewater treatment, posing potential risks to aquatic ecosystems and human health...

Using physiologically based pharmacokinetic modelling to optimize repaglinide and irbesartan dosing in Chinese population with SLCO1B1 polymorphism

Aim The first aim of this study was to develop physiologically based pharmacokinetic (PBPK) models for irbesartan (IRB) and repaglinide (REP) and then apply the REP/IRB PBPK model to describe the drug–drug interaction (DDI) of REP and IRB in the population with SLCO1B1 c.521 T &g...