Hongrui Zhang

Metabolic reprogramming and polarization of microglia in cerebral ischemia: the roles of mitochondria and inflammasomes

Mitochondrial dysfunction, metabolic reprogramming, and NLRP3 inflammasome activation have been widely studied in post-ischemic microglia. However, a systems-level understanding of how these three processes interact as a spatiotemporal regulatory network is lacking. Furthermore,...