Hongjie Wang

Tripartite motif protein 32 overexpression promotes inflammation and pyroptosis in INS-1 cells via the NF-κB/NLRP3 signaling pathway under high glucose conditions

Abstract Background: Type 2 diabetes mellitus (T2DM) is an inflammatory disease, and the primary features are insulin resistance and β-cell dysfunction. Inflammation and pyroptosis contribute to insulin resistance and β-cell dysfunction. Therefore, it is important to identify nov...