Hong Yu

The Immunomodulatory Effects of Mannan on the Fungicidal Activity of Macrophages Against Candidozyma auris Bloodstream Infection Associated with the GPCR-PI3K-NF-κB Signaling Pathway

Candidozyma auris is an emerging multidrug-resistant fungal pathogen, which causes high mortality and nosocomial outbreaks worldwide. Macrophages are key innate immune cells that clear fungi through phagocytosis, reactive oxygen species, and cytokine secretion. Mannan, a major fu...