Hong Jiang

Multifaceted Cross-Rational Modification of the α2,3-Sialyltransferase MsST for High-Efficiency Production of 3′-Sialyl-3-fucosyllactose via One-Pot Cascade Reaction

Abstract 3′-Sialyl-3-fucosyllactose (3′S3FL) is a representative fucose-containing sialylated human milk oligosaccharide with distinctive biological functions, but its in vitro synthesis is limited by the poor tolerance of α2,3-sialyltransferases toward fucosylated acceptors. Her...

Hierarchical Hybrid Assembly: Programming Structural Complexity in Crystalline Materials

Abstract The design of crystalline materials has evolved from the construction of periodic frameworks toward increasingly complex architectures featuring ordered heterogeneity and emergent functions. Despite substantial progress in hybrid crystalline materials, a general framewor...