Hisham A. Abbas

Disarming Pseudomonas aeruginosa: repurposing vardenafil, valsartan, and olmesartan as anti-virulence and antibiofilm agents

Abstract The rapid emergence of antibiotic resistance represents a critical global health challenge, particularly in biofilm-associated infections caused by Pseudomonas aeruginosa ( P. aeruginosa ). Quorum sensing plays a pivotal role in regulating bacterial virulence and biofilm...