Hiroyuki Arai

Activation of the endocytosis pathway stratifies subtypes and therapeutic sensitivity in colorectal cancer

Abstract Endocytosis regulates receptor trafficking and signaling, yet its role in colorectal cancer (CRC) remains unclear. We analyzed transcriptomic data from 15,025 CRC tumors to evaluate gene expression in clathrin-mediated endocytosis (CME) and the endosomal sorting complexe...