Hiroshi Imai

MxA expression in systemic lupus erythematosus –associated myocarditis indicates type I interferon pathway activation

Type I interferon (IFN) pathway activation plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Myxovirus resistance protein A (MxA) is a surrogate marker of type I IFN activity; however, evidence of local IFN pathway activation in myocarditis associ...