Hiromitsu Watanabe

Impact of baseline renal function on the clinical outcomes and safety of adjuvant nivolumab in high-risk urothelial carcinoma: a multicenter retrospective real-world study

Abstract Background Adjuvant nivolumab prolongs disease-free survival (DFS) in patients with urothelial carcinoma (UC) after radical surgery; however, evidence in those with reduced baseline renal function is limited. We investigated the impact of baseline creatinine clearance (C...

Real‐World Outcomes of Olaparib in Japanese Patients With BRCA ‐Mutated Metastatic Castration‐Resistant Prostate Cancer: Exploratory Analysis of BRCA2 Loss and Microsatellite Instability Status

OBJECTIVES: Metastatic castration-resistant prostate cancer has a poor prognosis. Although olaparib has demonstrated efficacy in patients with BRCA1/2 mutations, real-world data in Japanese patients remain limited. We aimed to evaluate the efficacy and safety of olaparib in patie...