Hiroki Taguchi

Safety of Endoscopic Ultrasound-Guided Biliary Drainage in Patients with Distal Malignant Biliary Obstruction with Large-Volume Ascites

Background/Aims: The safety and efficacy of endoscopic ultrasound-guided biliary drainage (EUS-BD) in patients with large-volume ascites (LVA) remain unclear. We aimed to evaluate the safety of EUS-BD in patients with distal malignant biliary obstruction complicated by LVA. Metho...

Relationship between initial dose, dose intensity, and survival in unresectable pancreatic cancer treated with nanoliposomal irinotecan, fluorouracil, and folinic acid

Abstract While nanoliposomal irinotecan with fluorouracil and folinic acid (NFF) is a standard second-line regimen for unresectable pancreatic cancer (uPC) after gemcitabine-based therapy, the effects of initial dosing and relative dose intensity (RDI) in routine practice are unc...

Promotion of Lead-induced Cytotoxicity in Differentiating Neural Cells and Protective Effects of Selenium

Lead (Pb) exposure remains a global health concern, particularly because of its adverse effects on neurodevelopment during fetal development and childhood. Early-life exposure to Pb during neuronal differentiation can impair neurodevelopment, although the underlying molecular mec...