Hirofumi Ota

Implementation status, difficulties, and barriers to adopting nursing-care technologies in long-term care facilities in Japan: A prefecture-wide cross-sectional survey

Background: Japan faces a shortage of care workers due to its rapidly aging population. Although nursing care technologies can reduce caregiver burden and improve care quality, their long-term feasibility remains unclear. We investigated the implementation of these technologies a...

Long-Term Survival Outcomes of Modified-FOLFOXIRI Plus Cetuximab Versus Bevacizumab in RAS / BRAF Wild-Type Metastatic Colorectal Cancer: Final Analysis of the DEEPER Trial

The randomized phase II DEEPER trial (jRCTs061180022) previously reported superior depth of response with modified 5-fluorouracil, leucovorin, oxaliplatin and irinotecan (m-FOLFOXIRI) plus cetuximab versus bevacizumab in patients with RAS wild-type metastatic colorectal cancer (m...