Hiroaki Ikematsu

Artificial dermis for protecting gastrointestinal mucosal defects: A feasibility study in ex vivo and in vivo porcine models

Although post-endoscopic submucosal dissection (ESD) mucosal defects can lead to delayed bleeding and perforation, an optimal protective method has not yet been established. This study aimed to evaluate the feasibility of using artificial dermis to protect against gastrointestina...

Gut microbial and metabolic biomarkers for early-onset colorectal cancer

Early-onset colorectal cancer (EO-CRC) is a growing global health challenge with poorly understood etiology. While gut microbiota and metabolites are implicated in colorectal carcinogenesis, EO-CRC-associated signatures remain poorly characterized. This study presents the first l...