Himanshu Joshi

Mechanistic insights into cooperative permeation of glycerol and water through human aquaporin-10

Human aquaporins are integral membrane proteins that facilitate transmembrane transport of small molecules. Among the 13 members of this family, pH-regulated human aquaporin-10 (hAQP10) plays a critical role in glycerol metabolism and lipid homeostasis. A molecular-level understa...